Antiherpesvirus Activities of (1′S,2′R)-9-{[1′,2′-Bis(hydroxymethyl)cycloprop-1′-yl]methyl}guanine (A-5021) in Cell Culture

Antiherpetic activity of (1′S,2′R)-9-{[1′,2′-bis(hydroxymethyl)cycloprop-1′-yl]methyl}guanine (A-5021) was compared with those of acyclovir (ACV) and penciclovir (PCV) in cell cultures. In a plaque reduction assay using a selection of human cells, A-5021 showed the most potent activity in all cells....

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Detalhes bibliográficos
Main Authors: Iwayama, Satoshi, Ono, Nobukazu, Ohmura, Yuko, Suzuki, Katsuya, Aoki, Miho, Nakazawa, Harumi, Oikawa, Miki, Kato, Tamamo, Okunishi, Masahiko, Nishiyama, Yukihiro, Yamanishi, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC105663/
https://ncbi.nlm.nih.gov/pubmed/9661001
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