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Suppression of herpes simplex virus type 1 reactivation from latency by (+-)-9-([(Z)-2-(hydroxymethyl)cyclohexyl]methyl) guanine (L-653,180) in vitro.

Latent herpes simplex virus type 1 (HSV-1) infection was induced in human embryonic lung cells in vitro by using a combination of viral replication inhibitors and elevated temperature. Under reactivating conditions (superinfection by human cytomegalovirus or temperature manipulation), a nonantiviral...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Nsiah, Y A, Tolman, R L, Karkas, J D, Rapp, F
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171871/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2171423/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.8.1551
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