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Human γ-globin gene promoter element regulates human β-globin gene developmental specificity

The persistence of fetal hemoglobin in many patients with deletion type β thalassemias and the expression patterns of human globin genes in transgenic mice suggest that γ- to β-globin gene switching results primarily from competition of γ- and β-globin genes for interaction with the β-globin locus c...

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Bibliografiske detaljer
Main Authors: Ryan, T. M., Sun, C.-W., Ren, Jinxiang, Townes, T. M.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC102642/
https://ncbi.nlm.nih.gov/pubmed/10908330
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