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Developmental specificity of recruitment of TBP to the TATA box of the human γ-globin gene

It is unclear whether the core promoter is involved in developmental regulation. To address this question, we mutated the TATA box of the human γ-globin gene, produced transgenic mice, and examined the effect of the mutation during the course of mouse development. In our test system, the γ-globin ge...

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Библиографические подробности
Главные авторы: Duan, Zhi-Jun, Fang, Xiangdong, Rohde, Alex, Han, Hemei, Stamatoyannopoulos, George, Li, Qiliang
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2002
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC122800/
https://ncbi.nlm.nih.gov/pubmed/11960008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.072084499
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