Identification of Id2 as a Globin Regulatory Protein by Representational Difference Analysis of K562 Cells Induced To Express γ-Globin with a Fungal Compound

A fungus-derived compound (OSI-2040) which induces fetal globin expression in the absence of erythroid cell differentiation was identified in a high-throughput drug discovery program. We utilized this compound to isolate γ-globin regulatory genes that are differentially expressed in OSI-2040-induced...

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Detalhes bibliográficos
Main Authors: Holmes, Melissa L., Haley, John D., Cerruti, Loretta, Zhou, Wen-lai, Zogos, Helen, Smith, David E., Cunningham, John M., Jane, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC104377/
https://ncbi.nlm.nih.gov/pubmed/10330158
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