Distinct Domains of Erythroid Krüppel-Like Factor Modulate Chromatin Remodeling and Transactivation at the Endogenous β-Globin Gene Promoter

Characterization of the mechanism(s) of action of trans-acting factors in higher eukaryotes requires the establishment of cellular models that test their function at endogenous target gene regulatory elements. Erythroid Krüppel-like factor (EKLF) is essential for β-globin gene transcription. To eluc...

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Main Authors: Brown, R. Clark, Pattison, Scott, van Ree, Janine, Coghill, Elise, Perkins, Andrew, Jane, Stephen M., Cunningham, John M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC134232/
https://ncbi.nlm.nih.gov/pubmed/11739731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.1.161-170.2002
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