Identification of Id2 as a Globin Regulatory Protein by Representational Difference Analysis of K562 Cells Induced To Express γ-Globin with a Fungal Compound

A fungus-derived compound (OSI-2040) which induces fetal globin expression in the absence of erythroid cell differentiation was identified in a high-throughput drug discovery program. We utilized this compound to isolate γ-globin regulatory genes that are differentially expressed in OSI-2040-induced...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Holmes, Melissa L., Haley, John D., Cerruti, Loretta, Zhou, Wen-lai, Zogos, Helen, Smith, David E., Cunningham, John M., Jane, Stephen M.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1999
Soggetti:	Transcriptional Regulation
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104377/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10330158/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.6.4182
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