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Developmental- and differentiation-specific patterns of human γ- and β-globin promoter DNA methylation
The mechanisms underlying the human fetal-to-adult β-globin gene switch remain to be determined. While there is substantial experimental evidence to suggest that promoter DNA methylation is involved in this process, most data come from studies in nonhuman systems. We have evaluated human γ- and β-gl...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society of Hematology
2007
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1939907/ https://ncbi.nlm.nih.gov/pubmed/17456718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-01-068635 |
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