Developmental- and differentiation-specific patterns of human γ- and β-globin promoter DNA methylation

The mechanisms underlying the human fetal-to-adult β-globin gene switch remain to be determined. While there is substantial experimental evidence to suggest that promoter DNA methylation is involved in this process, most data come from studies in nonhuman systems. We have evaluated human γ- and β-gl...

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Bibliographic Details
Main Authors: Mabaera, Rodwell, Richardson, Christine A., Johnson, Kristin, Hsu, Mei, Fiering, Steven, Lowrey, Christopher H.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2007
Subjects:
Red Cells
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1939907/
https://ncbi.nlm.nih.gov/pubmed/17456718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-01-068635
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