Developmentally-regulated extended domains of DNA hypomethylation encompass highly transcribed genes of the human β-globin locus

OBJECTIVE: DNA methylation has long been implicated in developmental β-globin gene regulation. However, the mechanism underlying this regulation is unclear, especially since these genes do not contain CpG islands. This has led us to propose and test the hypothesis that, just as for histone modificat...

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Main Authors: Lathrop, Melissa J., Hsu, Mei, Richardson, Christine A., Olivier, Emmanuel N., Bouhassira, Eric E., Fiering, Steven, Lowrey, Christopher H.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792488/
https://ncbi.nlm.nih.gov/pubmed/19460471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2009.04.005
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