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Developmentally Specific Role of the CCAAT Box in Regulation of Human γ-Globin Gene Expression

The CCAAT box is a widespread motif in eukaryotic promoters. In this study we demonstrate that the effects of the CCAAT box on γ-globin gene activation are developmentally distinct. Although this promoter element is essential for high level γ gene expression in adult erythropoiesis, it plays little...

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Detalhes bibliográficos
Main Authors: Fang, Xiangdong, Han, Hemei, Stamatoyannopoulos, George, Li, Qiliang
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808414/
https://ncbi.nlm.nih.gov/pubmed/14645237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M306241200
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