Genetic signature of histiocytic sarcoma revealed by a sleeping beauty transposon genetic screen in mice.

Histiocytic sarcoma is a rare, aggressive neoplasm that responds poorly to therapy. Histiocytic sarcoma is thought to arise from macrophage precursor cells via genetic changes that are largely undefined. To improve our understanding of the etiology of histiocytic sarcoma we conducted a forward genet...

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Main Authors: Raha A Been, Michael A Linden, Courtney J Hager, Krista J DeCoursin, Juan E Abrahante, Sean R Landman, Michael Steinbach, Aaron L Sarver, David A Largaespada, Timothy K Starr
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2014-01-01
叢編:PLoS ONE
在線閱讀:http://europepmc.org/articles/PMC4020815?pdf=render
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