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Transposons for cancer gene discovery: Sleeping Beauty and beyond

The use of Sleeping Beauty transposons as somatic mutagens to discover cancer genes in hematopoietic tumors and sarcomas has been documented. Here, we discuss the future of Sleeping Beauty for cancer genetic studies and the potential use of additional transposable elements for somatic mutagenesis.

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Collier, Lara S, Largaespada, David A
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2106843/
https://ncbi.nlm.nih.gov/pubmed/18047692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-s1-s15
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