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Transposons for cancer gene discovery: Sleeping Beauty and beyond

The use of Sleeping Beauty transposons as somatic mutagens to discover cancer genes in hematopoietic tumors and sarcomas has been documented. Here, we discuss the future of Sleeping Beauty for cancer genetic studies and the potential use of additional transposable elements for somatic mutagenesis.

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Detalles Bibliográficos
Autores principales: Collier, Lara S, Largaespada, David A
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2106843/
https://ncbi.nlm.nih.gov/pubmed/18047692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-s1-s15
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