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Transposons for cancer gene discovery: Sleeping Beauty and beyond
The use of Sleeping Beauty transposons as somatic mutagens to discover cancer genes in hematopoietic tumors and sarcomas has been documented. Here, we discuss the future of Sleeping Beauty for cancer genetic studies and the potential use of additional transposable elements for somatic mutagenesis.
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2106843/ https://ncbi.nlm.nih.gov/pubmed/18047692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-s1-s15 |
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