RNA sequencing of Sleeping Beauty transposon-induced tumors detects transposon-RNA fusions in forward genetic cancer screens

Forward genetic screens using Sleeping Beauty (SB)-mobilized T2/Onc transposons have been used to identify common insertion sites (CISs) associated with tumor formation. Recurrent sites of transposon insertion are commonly identified using ligation-mediated PCR (LM-PCR). Here, we use RNA sequencing...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Temiz, Nuri A., Moriarity, Branden S., Wolf, Natalie K., Riordan, Jesse D., Dupuy, Adam J., Largaespada, David A., Sarver, Aaron L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
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Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691744/
https://ncbi.nlm.nih.gov/pubmed/26553456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.188649.114
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