Genetic signature of histiocytic sarcoma revealed by a sleeping beauty transposon genetic screen in mice.

Histiocytic sarcoma is a rare, aggressive neoplasm that responds poorly to therapy. Histiocytic sarcoma is thought to arise from macrophage precursor cells via genetic changes that are largely undefined. To improve our understanding of the etiology of histiocytic sarcoma we conducted a forward genet...

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Main Authors: Raha A Been, Michael A Linden, Courtney J Hager, Krista J DeCoursin, Juan E Abrahante, Sean R Landman, Michael Steinbach, Aaron L Sarver, David A Largaespada, Timothy K Starr
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2014-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4020815?pdf=render
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