The Golgi as a “Proton Sink” in Cancer

Cancer cells exhibit increased glycolytic flux and adenosine triphosphate (ATP) hydrolysis. These processes increase the acidic burden on the cells through the production of lactate and protons. Nonetheless, cancer cells can maintain an alkaline intracellular pH (pHi) relative to untransformed cells...

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書目詳細資料

Principais autores:	Koen M. O. Galenkamp, Cosimo Commisso
格式:	Artigo
語言:	Inglês
出版:	Frontiers Media S.A. 2021-05-01
叢編:	Frontiers in Cell and Developmental Biology
主題:	Golgi pH proton sink pH homeostasis ion transport intracellular pH cancer
在線閱讀:	https://www.frontiersin.org/articles/10.3389/fcell.2021.664295/full
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