The Golgi as a “Proton Sink” in Cancer
Cancer cells exhibit increased glycolytic flux and adenosine triphosphate (ATP) hydrolysis. These processes increase the acidic burden on the cells through the production of lactate and protons. Nonetheless, cancer cells can maintain an alkaline intracellular pH (pHi) relative to untransformed cells...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2021-05-01
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| Collection: | Frontiers in Cell and Developmental Biology |
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| Accès en ligne: | https://www.frontiersin.org/articles/10.3389/fcell.2021.664295/full |
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