H+ and Pi Byproducts of Glycosylation Affect Ca2+ Homeostasis and Are Retrieved from the Golgi Complex by Homologs of TMEM165 and XPR1

Glycosylation reactions in the Golgi complex and the endoplasmic reticulum utilize nucleotide sugars as donors and produce inorganic phosphate (Pi) and acid (H+) as byproducts. Here we show that homologs of mammalian XPR1 and TMEM165 (termed Erd1 and Gdt1) recycle luminal Pi and exchange luminal H+...

Volledige beschrijving

Bibliografische gegevens

Hoofdauteurs:	Nathan A. Snyder, Christopher P. Stefan, Camille T. Soroudi, Adam Kim, Carlos Evangelista, Kyle W. Cunningham
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Oxford University Press 2017-12-01
Reeks:	G3: Genes, Genomes, Genetics
Onderwerpen:	Calcium homeostasis phosphate glycosylation Golgi complex
Online toegang:	http://g3journal.org/lookup/doi/10.1534/g3.117.300339
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!