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The Golgi as a “Proton Sink” in Cancer

Cancer cells exhibit increased glycolytic flux and adenosine triphosphate (ATP) hydrolysis. These processes increase the acidic burden on the cells through the production of lactate and protons. Nonetheless, cancer cells can maintain an alkaline intracellular pH (pHi) relative to untransformed cells...

詳細記述

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書誌詳細
主要な著者: Koen M. O. Galenkamp, Cosimo Commisso
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2021-05-01
シリーズ:Frontiers in Cell and Developmental Biology
主題:
オンライン・アクセス:https://www.frontiersin.org/articles/10.3389/fcell.2021.664295/full
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