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The Golgi as a “Proton Sink” in Cancer

Cancer cells exhibit increased glycolytic flux and adenosine triphosphate (ATP) hydrolysis. These processes increase the acidic burden on the cells through the production of lactate and protons. Nonetheless, cancer cells can maintain an alkaline intracellular pH (pHi) relative to untransformed cells...

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Bibliografiska uppgifter
Huvudupphov: Koen M. O. Galenkamp, Cosimo Commisso
Materialtyp: Artigo
Språk:Inglês
Utgiven: Frontiers Media S.A. 2021-05-01
Serie:Frontiers in Cell and Developmental Biology
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Länkar:https://www.frontiersin.org/articles/10.3389/fcell.2021.664295/full
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