In Vitro Hepatic Clearance Evaluations of Per- and Polyfluoroalkyl Substances (PFAS) across Multiple Structural Categories

Toxicokinetic (TK) assays and in vitro–in vivo extrapolation (IVIVE) models are New Approach Methods (NAMs) used to translate in vitro points of departure to exposure estimates required to reach equivalent blood concentrations. Per- and polyfluoroalkyl substances (PFAS) are a large chemical class wi...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	David M. Crizer, Julie R. Rice, Marci G. Smeltz, Katelyn S. Lavrich, Krishna Ravindra, John F. Wambaugh, Michael DeVito, Barbara A. Wetmore
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2024-09-01
Цуврал:	Toxics
Нөхцлүүд:	PFAS toxicokinetics (TK) hepatic clearance in vitro–in vivo extrapolation (IVIVE) New Approach Methods (NAMs) metabolism
Онлайн хандалт:	https://www.mdpi.com/2305-6304/12/9/672
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!