In Vitro Hepatic Clearance Evaluations of Per- and Polyfluoroalkyl Substances (PFAS) across Multiple Structural Categories

Toxicokinetic (TK) assays and in vitro–in vivo extrapolation (IVIVE) models are New Approach Methods (NAMs) used to translate in vitro points of departure to exposure estimates required to reach equivalent blood concentrations. Per- and polyfluoroalkyl substances (PFAS) are a large chemical class wi...

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Autori principali:	David M. Crizer, Julie R. Rice, Marci G. Smeltz, Katelyn S. Lavrich, Krishna Ravindra, John F. Wambaugh, Michael DeVito, Barbara A. Wetmore
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2024-09-01
Serie:	Toxics
Soggetti:	PFAS toxicokinetics (TK) hepatic clearance in vitro–in vivo extrapolation (IVIVE) New Approach Methods (NAMs) metabolism
Accesso online:	https://www.mdpi.com/2305-6304/12/9/672
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