In Vitro Hepatic Clearance Evaluations of Per- and Polyfluoroalkyl Substances (PFAS) across Multiple Structural Categories

Toxicokinetic (TK) assays and in vitro–in vivo extrapolation (IVIVE) models are New Approach Methods (NAMs) used to translate in vitro points of departure to exposure estimates required to reach equivalent blood concentrations. Per- and polyfluoroalkyl substances (PFAS) are a large chemical class wi...

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Ngā kaituhi matua:	David M. Crizer, Julie R. Rice, Marci G. Smeltz, Katelyn S. Lavrich, Krishna Ravindra, John F. Wambaugh, Michael DeVito, Barbara A. Wetmore
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	MDPI AG 2024-09-01
Rangatū:	Toxics
Ngā marau:	PFAS toxicokinetics (TK) hepatic clearance in vitro–in vivo extrapolation (IVIVE) New Approach Methods (NAMs) metabolism
Urunga tuihono:	https://www.mdpi.com/2305-6304/12/9/672
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!