In Vitro Hepatic Clearance Evaluations of Per- and Polyfluoroalkyl Substances (PFAS) across Multiple Structural Categories

Toxicokinetic (TK) assays and in vitro–in vivo extrapolation (IVIVE) models are New Approach Methods (NAMs) used to translate in vitro points of departure to exposure estimates required to reach equivalent blood concentrations. Per- and polyfluoroalkyl substances (PFAS) are a large chemical class wi...

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主要な著者:	David M. Crizer, Julie R. Rice, Marci G. Smeltz, Katelyn S. Lavrich, Krishna Ravindra, John F. Wambaugh, Michael DeVito, Barbara A. Wetmore
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2024-09-01
シリーズ:	Toxics
主題:	PFAS toxicokinetics (TK) hepatic clearance in vitro–in vivo extrapolation (IVIVE) New Approach Methods (NAMs) metabolism
オンライン･アクセス:	https://www.mdpi.com/2305-6304/12/9/672
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