In Vitro Hepatic Clearance Evaluations of Per- and Polyfluoroalkyl Substances (PFAS) across Multiple Structural Categories

Toxicokinetic (TK) assays and in vitro–in vivo extrapolation (IVIVE) models are New Approach Methods (NAMs) used to translate in vitro points of departure to exposure estimates required to reach equivalent blood concentrations. Per- and polyfluoroalkyl substances (PFAS) are a large chemical class wi...

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Bibliografische gegevens

Hoofdauteurs:	David M. Crizer, Julie R. Rice, Marci G. Smeltz, Katelyn S. Lavrich, Krishna Ravindra, John F. Wambaugh, Michael DeVito, Barbara A. Wetmore
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	MDPI AG 2024-09-01
Reeks:	Toxics
Onderwerpen:	PFAS toxicokinetics (TK) hepatic clearance in vitro–in vivo extrapolation (IVIVE) New Approach Methods (NAMs) metabolism
Online toegang:	https://www.mdpi.com/2305-6304/12/9/672
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