Using LDpred2 to adapt polygenic risk score techniques for methylation score creation
Abstract Objective This study sought to determine if the R package LDpred2, designed for polygenic risk score creation for genome-wide association studies using summary statistics, could be adapted for deriving DNA methylation scores from methylome-wide association studies. Recognizing that linkage...
Furkejuvvon:
| Váldodahkkit: | , , , , , , |
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| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
BMC
2025-04-01
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| Ráidu: | BMC Research Notes |
| Fáttát: | |
| Liŋkkat: | https://doi.org/10.1186/s13104-025-07222-2 |
| Fáddágilkorat: |
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