Optimizing and benchmarking polygenic risk scores with GWAS summary statistics
Abstract Background Polygenic risk score (PRS) is a major research topic in human genetics. However, a significant gap exists between PRS methodology and applications in practice due to often unavailable individual-level data for various PRS tasks including model fine-tuning, benchmarking, and ensem...
Furkejuvvon:
| Váldodahkkit: | , , , , , , , , |
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| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
BMC
2024-10-01
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| Ráidu: | Genome Biology |
| Fáttát: | |
| Liŋkkat: | https://doi.org/10.1186/s13059-024-03400-w |
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