The MprF homolog LysX synthesizes lysyl-diacylglycerol contributing to antibiotic resistance and virulence
ABSTRACT Lysyl-diacylglycerol (Lys-DAG) was identified three decades ago in Mycobacterium phlei, but the biosynthetic pathway and function of this aminoacylated lipid have since remained uncharacterized. Combining genetic methods, mass spectrometry, and biochemical approaches, we show that the multi...
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| Principais autores: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2023-10-01
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| Serier: | Microbiology Spectrum |
| Fag: | |
| Online adgang: | https://journals.asm.org/doi/10.1128/spectrum.01429-23 |
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