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The MprF homolog LysX synthesizes lysyl-diacylglycerol contributing to antibiotic resistance and virulence

ABSTRACT Lysyl-diacylglycerol (Lys-DAG) was identified three decades ago in Mycobacterium phlei, but the biosynthetic pathway and function of this aminoacylated lipid have since remained uncharacterized. Combining genetic methods, mass spectrometry, and biochemical approaches, we show that the multi...

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Detaylı Bibliyografya
Asıl Yazarlar: Cameron P. Gill, Christopher Phan, Vivien Platt, Danielle Worrell, Thomas Andl, Hervé Roy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2023-10-01
Seri Bilgileri:Microbiology Spectrum
Konular:
Online Erişim:https://journals.asm.org/doi/10.1128/spectrum.01429-23
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