The MprF homolog LysX synthesizes lysyl-diacylglycerol contributing to antibiotic resistance and virulence
ABSTRACT Lysyl-diacylglycerol (Lys-DAG) was identified three decades ago in Mycobacterium phlei, but the biosynthetic pathway and function of this aminoacylated lipid have since remained uncharacterized. Combining genetic methods, mass spectrometry, and biochemical approaches, we show that the multi...
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| Автори: | , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
American Society for Microbiology
2023-10-01
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| Серія: | Microbiology Spectrum |
| Предмети: | |
| Онлайн доступ: | https://journals.asm.org/doi/10.1128/spectrum.01429-23 |
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