6. Dose Adjustments Based on Pharmacogenetics of CYP450 Enzymes

por van Schaik, Ron H.N.
Publicado en EJIFCC (2008)

The CYP3A4*22 allele affects the predictive value of a pharmacogenetic algorithm predicting tacrolimus predose concentrations

por Elens, Laure, Hesselink, Dennis A, van Schaik, Ron H N, van Gelder, Teun
Publicado 2013

A Guide to the Current Web-Based Resources in Pharmacogenomics

por Glubb, Dylan M., Paugh, Steven W., van Schaik, Ron H.N., Innocenti, Federico
Publicado 2013

Pharmacogenetics in Psychiatry: An Update on Clinical Usability

por van Schaik, Ron H. N., Müller, Daniel J., Serretti, Alessandro, Ingelman-Sundberg, Magnus
Publicado en Front Pharmacol (2020)

Editorial: Liquid Biopsy as a Tool for Precision Oncology: New Challenges to Assess Clinical Response

por Ravegnini, Gloria, Del Re, Marzia, Grolla, Ambra A., van Schaik, Ron H. N., Angelini, Sabrina
Publicado en Front Pharmacol (2020)

Clinical implementation of pharmacogenetics in kidney transplantation: calcineurin inhibitors in the starting blocks

por Elens, Laure, Bouamar, Rachida, Shuker, Nauras, Hesselink, Dennis A, van Gelder, Teun, van Schaik, Ron H N
Publicado 2014

Effect of Short-Term Fasting on Systemic Cytochrome P450-Mediated Drug Metabolism in Healthy Subjects: A Randomized, Controlled, Crossover Study Using a Cocktail Approach

por Lammers, Laureen A., Achterbergh, Roos, van Schaik, Ron H. N., Romijn, Johannes A., Mathôt, Ron A. A.
Publicado en Clin Pharmacokinet (2017)

Dihydropyrimidine dehydrogenase polymorphisms and fluoropyrimidine toxicity: ready for routine clinical application within personalized medicine?

por Del Re, Marzia, Di Paolo, Antonello, van Schaik, Ron H., Bocci, Guido, Simi, Paolo, Falcone, Alfredo, Danesi, Romano
Publicado 2010

Key challenges for next-generation pharmacogenomics

por Kampourakis, Kostas, Vayena, Effy, Mitropoulou, Christina, van Schaik, Ron H, Cooper, David N, Borg, Joseph, Patrinos, George P
Publicado 2014

Enantioselective pharmacokinetics of tramadol and its three main metabolites; impact of CYP2D6, CYP2B6, and CYP3A4 genotype

por Haage, Pernilla, Kronstrand, Robert, Josefsson, Martin, Calistri, Simona, van Schaik, Ron H. N., Green, Henrik, Kugelberg, Fredrik C.
Publicado en Pharmacol Res Perspect (2018)

Individualization of Irinotecan Treatment: A Review of Pharmacokinetics, Pharmacodynamics, and Pharmacogenetics

por de Man, Femke M., Goey, Andrew K. L., van Schaik, Ron H. N., Mathijssen, Ron H. J., Bins, Sander
Publicado en Clin Pharmacokinet (2018)

Genetic Variation in the Multidrug and Toxin Extrusion 1 Transporter Protein Influences the Glucose-Lowering Effect of Metformin in Patients With Diabetes: A Preliminary Study

por Becker, Matthijs L., Visser, Loes E., van Schaik, Ron H.N., Hofman, Albert, Uitterlinden, André G., Stricker, Bruno H.Ch.
Publicado 2009

Can TDM Improve Pharmacotherapy of HIV Infection in Adolescents?

por Rakhmanina, Natella Y., van den Anker, John N., Soldin, Steven J., van Schaik, Ron H., Mordwinkin, Nick, Neely, Michael N.
Publicado 2010

OCT1 polymorphism is associated with response and survival time in anti-Parkinsonian drug users

por Becker, Matthijs L., Visser, Loes E., van Schaik, Ron H. N., Hofman, Albert, Uitterlinden, André G., Stricker, Bruno H. Ch.
Publicado 2010

Clinical CYP2D6 Genotyping to Personalize Adjuvant Tamoxifen Treatment in ER-Positive Breast Cancer Patients: Current Status of a Controversy

por Mulder, Tessa A. M., de With, Mirjam, del Re, Marzia, Danesi, Romano, Mathijssen, Ron H. J., van Schaik, Ron H. N.
Publicado en Cancers (Basel) (2021)

Golden Helix Institute of Biomedical Research: Interdisciplinary research and educational activities in pharmacogenomics and personalized medicine

por Mitropoulos, Konstantinos, Innocenti, Federico, van Schaik, Ron H., Lezhava, Alexander, Tzimas, Giannis, Kollia, Panagoula, Macek, Milan, Fortina, Paolo, Patrinos, George P.
Publicado 2012

Polymorphisms in type I and II inosine monophosphate dehydrogenase genes and association with clinical outcome in patients on mycophenolate mofetil

por Gensburger, Olivier, Van Schaik, Ron H. N., Picard, Nicolas, Le Meur, Yannick, Rousseau, Annick, Woillard, Jean-Baptiste, Van Gelder, Teun, Marquet, Pierre
Publicado 2010

Differences in CYP3A genotypes of a liver transplant recipient and the donor liver graft and adjustment of tacrolimus dose

por Berger, Florine A., Mulder, Midas B., ten Bosch‐Dijksman, Willemijn, van Schaik, Ron H.N., Coenen, Sandra, de Winter, Brenda C.M.
Publicado en Br J Clin Pharmacol (2019)

Influence of the CYP2D6*4 polymorphism on dose, switching and discontinuation of antidepressants

por Bijl, Monique J, Visser, Loes E, Hofman, Albert, Vulto, Arnold G, van Gelder, Teun, Stricker, Bruno H Ch, van Schaik, Ron H N
Publicado 2008

CYP3A5, ABCB1 and SLCO1B1 Polymorphisms and Pharmacokinetics and Virologic Outcome of Lopinavir/Ritonavir in HIV-infected Children

por Rakhmanina, Natella Y., Neely, Michael, Van Schaik, Ron H.N., Gordish-Dressman, Heather, Williams, Keetra D., Soldin, Steven J., van den Anker, John N.
Publicado 2011