Drug interactions may be important risk factors for methotrexate neurotoxicity, particularly in pediatric leukemia patients

por Forster, Victoria J., van Delft, Frederik W., Baird, Susan F., Mair, Shona, Skinner, Roderick, Halsey, Christina
Publicado en Cancer Chemother Pharmacol (2016)

Genetic and Functional Diversity of Propagating Cells in Glioblastoma

por Piccirillo, Sara G.M., Colman, Sue, Potter, Nicola E., van Delft, Frederik W., Lillis, Suzanne, Carnicer, Maria-Jose, Kearney, Lyndal, Watts, Colin, Greaves, Mel
Publicado en Stem Cell Reports (2014)

Developmental origins and impact of BCR-ABL1 fusion and IKZF1 deletions in monozygotic twins with Ph(+) acute lymphoblastic leukemia

por Cazzaniga, Giovanni, van Delft, Frederik W., Lo Nigro, Luca, Ford, Anthony M., Score, Joannah, Iacobucci, Ilaria, Mirabile, Elena, Taj, Mary, Colman, Susan M., Biondi, Andrea, Greaves, Mel
Publicado 2011

Phase II-like murine trial identifies synergy between dexamethasone and dasatinib in T-cell acute lymphoblastic leukemia

por Shi, Yuzhe, Beckett, Melanie C., Blair, Helen J., Tirtakusuma, Ricky, Nakjang, Sirintra, Enshaei, Amir, Halsey, Christina, Vormoor, Josef, Heidenreich, Olaf, Krippner-Heidenreich, Anja, van Delft, Frederik W.
Publicado en Haematologica (2020)

Immunologically silent cancer clone transmission from mother to offspring

por Isoda, Takeshi, Ford, Anthony M., Tomizawa, Daisuke, van Delft, Frederik W., De Castro, David Gonzalez, Mitsuiki, Norkio, Score, Joannah, Taki, Tomohiko, Morio, Tomohiro, Takagi, Masatoshi, Saji, Hiroh, Greaves, Mel, Mizutani, Shuki
Publicado 2009

Complex genomic alterations and gene expression in acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21

por Strefford, Jon C., van Delft, Frederik W., Robinson, Hazel M., Worley, Helen, Yiannikouris, Olga, Selzer, Rebecca, Richmond, Todd, Hann, Ian, Bellotti, Tony, Raghavan, Manoj, Young, Bryan D., Saha, Vaskar, Harrison, Christine J.
Publicado 2006

Modeling the evolution of ETV6-RUNX1-induced B-cell precursor acute lymphoblastic leukemia in mice

por van der Weyden, Louise, Giotopoulos, George, Rust, Alistair G., Matheson, Louise S., van Delft, Frederik W., Kong, Jun, Corcoran, Anne E., Greaves, Mel F., Mullighan, Charles G., Huntly, Brian J., Adams, David J.
Publicado 2011

Distinctive genotypes in infants with T‐cell acute lymphoblastic leukaemia

por Mansur, Marcela B., van Delft, Frederik W., Colman, Susan M., Furness, Caroline L., Gibson, Jane, Emerenciano, Mariana, Kempski, Helena, Clappier, Emmanuelle, Cave, Hélène, Soulier, Jean, Pombo‐de‐Oliveira, Maria S., Greaves, Mel, Ford, Anthony M.
Publicado en Br J Haematol (2015)

Label‐Free Leukemia Monitoring by Computer Vision

por Doan, Minh, Case, Marian, Masic, Dino, Hennig, Holger, McQuin, Claire, Caicedo, Juan, Singh, Shantanu, Goodman, Allen, Wolkenhauer, Olaf, Summers, Huw D., Jamieson, David, van Delft, Frederik W, Filby, Andrew, Carpenter, Anne E., Rees, Paul, Irving, Julie
Publicado en Cytometry A (2020)

A dyad of lymphoblastic lysosomal cysteine proteases degrades the antileukemic drug l-asparaginase

por Patel, Naina, Krishnan, Shekhar, Offman, Marc N., Krol, Marcin, Moss, Catherine X., Leighton, Carly, van Delft, Frederik W., Holland, Mark, Liu, JiZhong, Alexander, Seema, Dempsey, Clare, Ariffin, Hany, Essink, Monika, Eden, Tim O.B., Watts, Colin, Bates, Paul A., Saha, Vaskar
Publicado 2009

The subclonal complexity of STIL-TAL1+ T-cell acute lymphoblastic leukaemia

por Furness, Caroline L, Mansur, Marcela B, Weston, Victoria J, Ermini, Luca, van Delft, Frederik W, Jenkinson, Sarah, Gale, Rosemary, Harrison, Christine J, Pombo-de-Oliveira, Maria S, Sanchez-Martin, Marta, Ferrando, Adolfo A, Kearns, Pamela, Titley, Ian, Ford, Anthony M, Potter, Nicola E, Greaves, Mel
Publicado en Leukemia (2018)

The genomic landscape of teenage and young adult T‐cell acute lymphoblastic leukemia

por Mansur, Marcela B., Furness, Caroline L., Nakjang, Sirintra, Enshaei, Amir, Alpar, Donat, Colman, Sue M., Minto, Lynne, Irving, Julie, Poole, Beth V., Noronha, Elda P., Savola, Suvi, Iqbal, Sameena, Gribben, John, Pombo‐de‐Oliveira, Maria S., Ford, Tony M., Greaves, Mel F., van Delft, Frederik W.
Publicado en Cancer Med (2021)

RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia

por Papaemmanuil, Elli, Rapado, Inmaculada, Li, Yilong, Potter, Nicola E, Wedge, David C, Tubio, Jose, Alexandrov, Ludmil B, Van Loo, Peter, Cooke, Susanna L, Marshall, John, Martincorena, Inigo, Hinton, Jonathan, Gundem, Gunes, van Delft, Frederik W, Nik-Zainal, Serena, Jones, David R, Ramakrishna, Manasa, Titley, Ian, Stebbings, Lucy, Leroy, Catherine, Menzies, Andrew, Gamble, John, Robinson, Ben, Mudie, Laura, Raine, Keiran, O’Meara, Sarah, Teague, Jon W, Butler, Adam P, Cazzaniga, Giovanni, Biondi, Andrea, Zuna, Jan, Kempski, Helena, Muschen, Markus, Ford, Anthony M, Stratton, Michael R, Greaves, Mel, Campbell, Peter J
Publicado 2014

RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia

por Matthijssens, Filip, Sharma, Nitesh D., Nysus, Monique, Nickl, Christian K., Kang, Huining, Perez, Dominique R., Lintermans, Beatrice, Van Loocke, Wouter, Roels, Juliette, Peirs, Sofie, Demoen, Lisa, Pieters, Tim, Reunes, Lindy, Lammens, Tim, De Moerloose, Barbara, Van Nieuwerburgh, Filip, Deforce, Dieter L., Cheung, Laurence C., Kotecha, Rishi S., Risseeuw, Martijn D.P., Van Calenbergh, Serge, Takarada, Takeshi, Yoneda, Yukio, van Delft, Frederik W., Lock, Richard B., Merkley, Seth D., Chigaev, Alexandre, Sklar, Larry A., Mullighan, Charles G., Loh, Mignon L., Winter, Stuart S., Hunger, Stephen P., Goossens, Steven, Castillo, Eliseo F., Ornatowski, Wojciech, Van Vlierberghe, Pieter, Matlawska-Wasowska, Ksenia
Publicado en J Clin Invest (2021)