Modeling Unique Patients in Humanized Mice: Toward a Curative Strategy for HIV

Por Dorner, Marcus, de Jong, Ype P.
Publicado no Mol Ther (2018)

Animal models for the study of HCV

Por Vercauteren, Koen, de Jong, Ype P., Meuleman, Philip
Publicado no Curr Opin Virol (2015)

New horizons for studying human hepatotropic infections

Por de Jong, Ype P., Rice, Charles M., Ploss, Alexander
Publicado em 2010

Virus associated malignancies: The role of viral hepatitis in hepatocellular carcinoma

Por Shlomai, Amir, de Jong, Ype P., Rice, Charles M.
Publicado em 2014

The Balance between CD8(+) T Cell-Mediated Clearance of AAV-Encoded Antigen in the Liver and Tolerance Is Dependent on the Vector Dose

Por Kumar, Sandeep R.P., Hoffman, Brad E., Terhorst, Cox, de Jong, Ype P., Herzog, Roland W.
Publicado no Mol Ther (2017)

Human occludin is a hepatitis C virus entry factor required for infection of mouse cells

Por Ploss, Alexander, Evans, Matthew J., Gaysinskaya, Valeriya A., Panis, Maryline, You, Hana, de Jong, Ype P., Rice, Charles M.
Publicado em 2009

Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems

Por Shlomai, Amir, Schwartz, Robert E., Ramanan, Vyas, Bhatta, Ankit, de Jong, Ype P., Bhatia, Sangeeta N., Rice, Charles M.
Publicado em 2014

T Cell–mediated Pathology in Two Models of Experimental Colitis Depends Predominantly on the Interleukin 12/Signal Transducer and Activator of Transcription (Stat)-4 Pathway, but I...

Por Simpson, Stephen J., Shah, Samir, Comiskey, Martina, de Jong, Ype P., Wang, Baoping, Mizoguchi, Emiko, Bhan, Atul K., Terhorst, Cox
Publicado em 1998

Dynamics of antigen presentation to transgene product-specific CD4(+) T cells and of Treg induction upon hepatic AAV gene transfer

Por Perrin, George Q, Zolotukhin, Irene, Sherman, Alexandra, Biswas, Moanaro, de Jong, Ype P, Terhorst, Cox, Davidoff, Andrew M, Herzog, Roland W
Publicado no Mol Ther Methods Clin Dev (2016)

High- and low-affinity single-peptide/MHC ligands have distinct effects on the development of mucosal CD8αα and CD8αβ T lymphocytes

Por Levelt, Christiaan N., de Jong, Ype P., Mizoguchi, Emiko, O’Farrelly, Cliona, Bhan, Atul K., Tonegawa, Susumu, Terhorst, Cox, Simpson, Stephen J.
Publicado em 1999

A robust cell culture system supporting the complete life cycle of hepatitis B virus

Por Michailidis, Eleftherios, Pabon, Jonathan, Xiang, Kuanhui, Park, Paul, Ramanan, Vyas, Hoffmann, Hans-Heinrich, Schneider, William M., Bhatia, Sangeeta N., de Jong, Ype P., Shlomai, Amir, Rice, Charles M.
Publicado no Sci Rep (2017)

Analysis of Hepatitis C Virus Particle Heterogeneity in Immunodeficient Human Liver Chimeric fah-/- Mice

Por Andreo, Ursula, de Jong, Ype P., Scull, Margaret A., Xiao, Jing W., Vercauteren, Koen, Quirk, Corrine, Mommersteeg, Michiel C., Bergaya, Sonia, Menon, Arjun, Fisher, Edward A., Rice, Charles M.
Publicado no Cell Mol Gastroenterol Hepatol (2017)

Use of Spoligotyping and Large Sequence Polymorphisms To Study the Population Structure of the Mycobacterium tuberculosis Complex in a Cohort Study of Consecutive Smear-Positive Tu...

Por de Jong, Bouke C., Antonio, Martin, Awine, Timothy, Ogungbemi, Kunle, de Jong, Ype P., Gagneux, Sebastien, DeRiemer, Kathryn, Zozio, Thierry, Rastogi, Nalin, Borgdorff, Martien, Hill, Philip C., Adegbola, Richard A.
Publicado em 2009

The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity

Por Mendoza, Juan L., Schneider, William M., Hoffmann, Hans-Heinrich, Vercauteren, Koen, Jude, Kevin M., Xiong, Anming, Moraga, Ignacio, Horton, Tim M., Glenn, Jeffrey S., de Jong, Ype P., Rice, Charles M., Garcia, K. Christopher
Publicado no Immunity (2017)

Superior In vivo Transduction of Human Hepatocytes Using Engineered AAV3 Capsid

Por Vercauteren, Koen, Hoffman, Brad E, Zolotukhin, Irene, Keeler, Geoffrey D, Xiao, Jing W, Basner-Tschakarjan, Etiena, High, Katherine A, Ertl, Hildegund CJ, Rice, Charles M, Srivastava, Arun, de Jong, Ype P, Herzog, Roland W
Publicado no Mol Ther (2016)

Humanized mice efficiently engrafted with fetal hepatoblasts and syngeneic immune cells develop human monocytes and NK cells

Por Billerbeck, Eva, Mommersteeg, Michiel C., Shlomai, Amir, Xiao, Jing W., Andrus, Linda, Bhatta, Ankit, Vercauteren, Koen, Michailidis, Eleftherios, Dorner, Marcus, Krishnan, Anuradha, Charlton, Michael R., Chiriboga, Luis, Rice, Charles M., de Jong, Ype P.
Publicado no J Hepatol (2016)

Hepatitis C virus RNA functionally sequesters miR-122

Por Luna, Joseph M., Scheel, Troels K. H., Danino, Tal, Shaw, Katharina S., Mele, Aldo, Fak, John J., Nishiuchi, Eiko, Takacs, Constantin N., Catanese, Maria Teresa, de Jong, Ype P., Jacobson, Ira M., Rice, Charles M., Darnell, Robert B.
Publicado no Cell (2015)

Hepatitis C Virus Infects Rhesus Macaque Hepatocytes and Simianized Mice

Por Scull, Margaret A., Shi, Chao, de Jong, Ype P., Gerold, Gisa, Ries, Moritz, von Schaewen, Markus, Donovan, Bridget M., Labitt, Rachael N., Horwitz, Joshua A., Gaska, Jenna M., Hrebikova, Gabriela, Xiao, Jing W., Flatley, Brenna, Fung, Canny, Chiriboga, Luis, Walker, Christopher M., Evans, David T., Rice, Charles M., Ploss, Alexander
Publicado no Hepatology (2015)

Broadly neutralizing antibodies abrogate established hepatitis C virus infection

Por de Jong, Ype P., Dorner, Marcus, Mommersteeg, Michiel C., Xiao, Jing W., Balazs, Alejandro B., Robbins, Justin B., Winer, Benjamin Y., Gerges, Sherif, Vega, Kevin, Labitt, Rachael N., Donovan, Bridget M., Giang, Erick, Krishnan, Anuradha, Chiriboga, Luis, Charlton, Michael R., Burton, Dennis R., Baltimore, David, Law, Mansun, Rice, Charles M., Ploss, Alexander
Publicado no Sci Transl Med (2014)