Humanized mice efficiently engrafted with fetal hepatoblasts and syngeneic immune cells develop human monocytes and NK cells

BACKGROUND & AIMS: Human liver chimeric mice are useful models of human hepatitis virus infection, including hepatitis B and C virus infections. Independently, immunodeficient mice reconstituted with CD34(+) hematopoietic stem cells (HSC) derived from fetal liver reliably develop human T and B l...

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Detalhes bibliográficos
Publicado no:J Hepatol
Main Authors: Billerbeck, Eva, Mommersteeg, Michiel C., Shlomai, Amir, Xiao, Jing W., Andrus, Linda, Bhatta, Ankit, Vercauteren, Koen, Michailidis, Eleftherios, Dorner, Marcus, Krishnan, Anuradha, Charlton, Michael R., Chiriboga, Luis, Rice, Charles M., de Jong, Ype P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955758/
https://ncbi.nlm.nih.gov/pubmed/27151182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2016.04.022
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