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Human occludin is a hepatitis C virus entry factor required for infection of mouse cells

Hepatitis C virus (HCV) is a leading cause of liver disease worldwide. The development of much needed specific antiviral therapies and an effective vaccine has been hampered by the lack of a convenient small animal model. The determinants restricting HCV tropism to human and chimpanzee hosts are unk...

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Detalhes bibliográficos
Main Authors: Ploss, Alexander, Evans, Matthew J., Gaysinskaya, Valeriya A., Panis, Maryline, You, Hana, de Jong, Ype P., Rice, Charles M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762424/
https://ncbi.nlm.nih.gov/pubmed/19182773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07684
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