Nucleotide precursors prevent folic acid-resistant neural tube defects in the mouse

le Leung, Kit-Yi, De Castro, Sandra C.P., Savery, Dawn, Copp, Andrew J., Greene, Nicholas D.E.
Foilsithe 2013

Glycine Cleavage System H Protein Is Essential for Embryonic Viability, Implying Additional Function Beyond the Glycine Cleavage System

le Leung, Kit-Yi, De Castro, Sandra C. P., Galea, Gabriel L., Copp, Andrew J., Greene, Nicholas D. E.
Foilsithe in Front Genet (2021)

Folate metabolite profiling of different cell types and embryos suggests variation in folate one-carbon metabolism, including developmental changes in human embryonic brain

le Leung, Kit-Yi, De Castro, Sandra C. P., Cabreiro, Filipe, Gustavsson, Peter, Copp, Andrew J., Greene, Nicholas D. E.
Foilsithe 2013

Lamin B1 Polymorphism Influences Morphology of the Nuclear Envelope, Cell Cycle Progression, and Risk of Neural Tube Defects in Mice

le De Castro, Sandra C. P., Malhas, Ashraf, Leung, Kit-Yi, Gustavsson, Peter, Vaux, David J., Copp, Andrew J., Greene, Nicholas D. E.
Foilsithe 2012

Neural tube closure depends on expression of Grainyhead-like 3 in multiple tissues

le De Castro, Sandra C.P., Hirst, Caroline S., Savery, Dawn, Rolo, Ana, Lickert, Heiko, Andersen, Bogi, Copp, Andrew J., Greene, Nicholas D.E.
Foilsithe in Dev Biol (2018)

Formate supplementation enhances folate-dependent nucleotide biosynthesis and prevents spina bifida in a mouse model of folic acid-resistant neural tube defects

le Sudiwala, Sonia, De Castro, Sandra C.P., Leung, Kit-Yi, Brosnan, John T., Brosnan, Margaret E., Mills, Kevin, Copp, Andrew J., Greene, Nicholas D.E.
Foilsithe in Biochimie (2016)

Regulation of cell protrusions by small GTPases during fusion of the neural folds

le Rolo, Ana, Savery, Dawn, Escuin, Sarah, de Castro, Sandra C, Armer, Hannah EJ, Munro, Peter MG, Molè, Matteo A, Greene, Nicholas DE, Copp, Andrew J
Foilsithe in eLife (2016)

Spinal neural tube closure depends on regulation of surface ectoderm identity and biomechanics by Grhl2

le Nikolopoulou, Evanthia, Hirst, Caroline S., Galea, Gabriel, Venturini, Christina, Moulding, Dale, Marshall, Abigail R., Rolo, Ana, De Castro, Sandra C. P., Copp, Andrew J., Greene, Nicholas D. E.
Foilsithe in Nat Commun (2019)

Cellular mechanisms underlying Pax3-related neural tube defects and their prevention by folic acid

le Sudiwala, Sonia, Palmer, Alexandra, Massa, Valentina, Burns, Alan J., Dunlevy, Louisa P. E., de Castro, Sandra C. P., Savery, Dawn, Leung, Kit-Yi, Copp, Andrew J., Greene, Nicholas D. E.
Foilsithe in Dis Model Mech (2019)

Dynamic acetylation profile during mammalian neurulation

le Massa, Valentina, Avagliano, Laura, Grazioli, Paolo, De Castro, Sandra C. P., Parodi, Chiara, Savery, Dawn, Vergani, Patrizia, Cuttin, Serena, Doi, Patrizia, Bulfamante, Gaetano, Copp, Andrew J., Greene, Nicholas D. E.
Foilsithe in Birth Defects Res (2019)

Integrin-Mediated Focal Anchorage Drives Epithelial Zippering during Mouse Neural Tube Closure

le Molè, Matteo A., Galea, Gabriel L., Rolo, Ana, Weberling, Antonia, Nychyk, Oleksandr, De Castro, Sandra C., Savery, Dawn, Fässler, Reinhard, Ybot-González, Patricia, Greene, Nicholas D.E., Copp, Andrew J.
Foilsithe in Dev Cell (2020)

Overexpression of Grainyhead-like 3 causes spina bifida and interacts genetically with mutant alleles of Grhl2 and Vangl2 in mice

le De Castro, Sandra C P, Gustavsson, Peter, Marshall, Abigail R, Gordon, William M, Galea, Gabriel, Nikolopoulou, Evanthia, Savery, Dawn, Rolo, Ana, Stanier, Philip, Andersen, Bogi, Copp, Andrew J, Greene, Nicholas D E
Foilsithe in Hum Mol Genet (2018)

Diffusion microscopic MRI of the mouse embryo: Protocol and practical implementation in the splotch mouse model

le Norris, Francesca C., Siow, Bernard M., Cleary, Jon O., Wells, Jack A., De Castro, Sandra C.P., Ordidge, Roger J., Greene, Nicholas D.E., Copp, Andrew J., Scambler, Peter J., Alexander, Daniel. C., Lythgoe, Mark F.
Foilsithe in Magn Reson Med (2014)

Over-expression of Grhl2 causes spina bifida in the Axial defects mutant mouse

le Brouns, Madeleine R., De Castro, Sandra C.P., Terwindt-Rouwenhorst, Els A., Massa, Valentina, Hekking, Johan W., Hirst, Caroline S., Savery, Dawn, Munts, Chantal, Partridge, Darren, Lamers, Wout, Köhler, Eleonore, van Straaten, Henny W., Copp, Andrew J., Greene, Nicholas D.E.
Foilsithe 2011

SOX2 Plays a Critical Role in the Pituitary, Forebrain, and Eye during Human Embryonic Development

le Kelberman, Daniel, de Castro, Sandra C. P., Huang, Shuwen, Crolla, John A., Palmer, Rodger, Gregory, John W., Taylor, David, Cavallo, Luciano, Faienza, Maria F., Fischetto, Rita, Achermann, John C., Martinez-Barbera, Juan Pedro, Rizzoti, Karine, Lovell-Badge, Robin, Robinson, Iain C. A. F., Gerrelli, Dianne, Dattani, Mehul T.
Foilsithe 2008

Mutations in Radial Spoke Head Protein Genes RSPH9 and RSPH4A Cause Primary Ciliary Dyskinesia with Central-Microtubular-Pair Abnormalities

le Castleman, Victoria H., Romio, Leila, Chodhari, Rahul, Hirst, Robert A., de Castro, Sandra C.P., Parker, Keith A., Ybot-Gonzalez, Patricia, Emes, Richard D., Wilson, Stephen W., Wallis, Colin, Johnson, Colin A., Herrera, Rene J., Rutman, Andrew, Dixon, Mellisa, Shoemark, Amelia, Bush, Andrew, Hogg, Claire, Gardiner, R. Mark, Reish, Orit, Greene, Nicholas D.E., O'Callaghan, Christopher, Purton, Saul, Chung, Eddie M.K., Mitchison, Hannah M.
Foilsithe 2009

Mutations in ZMYND10, a Gene Essential for Proper Axonemal Assembly of Inner and Outer Dynein Arms in Humans and Flies, Cause Primary Ciliary Dyskinesia

le Moore, Daniel J., Onoufriadis, Alexandros, Shoemark, Amelia, Simpson, Michael A., zur Lage, Petra I., de Castro, Sandra C., Bartoloni, Lucia, Gallone, Giuseppe, Petridi, Stavroula, Woollard, Wesley J., Antony, Dinu, Schmidts, Miriam, Didonna, Teresa, Makrythanasis, Periklis, Bevillard, Jeremy, Mongan, Nigel P., Djakow, Jana, Pals, Gerard, Lucas, Jane S., Marthin, June K., Nielsen, Kim G., Santoni, Federico, Guipponi, Michel, Hogg, Claire, Antonarakis, Stylianos E., Emes, Richard D., Chung, Eddie M.K., Greene, Nicholas D.E., Blouin, Jean-Louis, Jarman, Andrew P., Mitchison, Hannah M.
Foilsithe 2013