Nucleotide precursors prevent folic acid-resistant neural tube defects in the mouse

Por Leung, Kit-Yi, De Castro, Sandra C.P., Savery, Dawn, Copp, Andrew J., Greene, Nicholas D.E.
Publicado em 2013

Glycine Cleavage System H Protein Is Essential for Embryonic Viability, Implying Additional Function Beyond the Glycine Cleavage System

Por Leung, Kit-Yi, De Castro, Sandra C. P., Galea, Gabriel L., Copp, Andrew J., Greene, Nicholas D. E.
Publicado no Front Genet (2021)

Folate metabolite profiling of different cell types and embryos suggests variation in folate one-carbon metabolism, including developmental changes in human embryonic brain

Por Leung, Kit-Yi, De Castro, Sandra C. P., Cabreiro, Filipe, Gustavsson, Peter, Copp, Andrew J., Greene, Nicholas D. E.
Publicado em 2013

Lamin B1 Polymorphism Influences Morphology of the Nuclear Envelope, Cell Cycle Progression, and Risk of Neural Tube Defects in Mice

Por De Castro, Sandra C. P., Malhas, Ashraf, Leung, Kit-Yi, Gustavsson, Peter, Vaux, David J., Copp, Andrew J., Greene, Nicholas D. E.
Publicado em 2012

Neural tube closure depends on expression of Grainyhead-like 3 in multiple tissues

Por De Castro, Sandra C.P., Hirst, Caroline S., Savery, Dawn, Rolo, Ana, Lickert, Heiko, Andersen, Bogi, Copp, Andrew J., Greene, Nicholas D.E.
Publicado no Dev Biol (2018)

Formate supplementation enhances folate-dependent nucleotide biosynthesis and prevents spina bifida in a mouse model of folic acid-resistant neural tube defects

Por Sudiwala, Sonia, De Castro, Sandra C.P., Leung, Kit-Yi, Brosnan, John T., Brosnan, Margaret E., Mills, Kevin, Copp, Andrew J., Greene, Nicholas D.E.
Publicado no Biochimie (2016)

Regulation of cell protrusions by small GTPases during fusion of the neural folds

Por Rolo, Ana, Savery, Dawn, Escuin, Sarah, de Castro, Sandra C, Armer, Hannah EJ, Munro, Peter MG, Molè, Matteo A, Greene, Nicholas DE, Copp, Andrew J
Publicado no eLife (2016)

Spinal neural tube closure depends on regulation of surface ectoderm identity and biomechanics by Grhl2

Por Nikolopoulou, Evanthia, Hirst, Caroline S., Galea, Gabriel, Venturini, Christina, Moulding, Dale, Marshall, Abigail R., Rolo, Ana, De Castro, Sandra C. P., Copp, Andrew J., Greene, Nicholas D. E.
Publicado no Nat Commun (2019)

Cellular mechanisms underlying Pax3-related neural tube defects and their prevention by folic acid

Por Sudiwala, Sonia, Palmer, Alexandra, Massa, Valentina, Burns, Alan J., Dunlevy, Louisa P. E., de Castro, Sandra C. P., Savery, Dawn, Leung, Kit-Yi, Copp, Andrew J., Greene, Nicholas D. E.
Publicado no Dis Model Mech (2019)

Dynamic acetylation profile during mammalian neurulation

Por Massa, Valentina, Avagliano, Laura, Grazioli, Paolo, De Castro, Sandra C. P., Parodi, Chiara, Savery, Dawn, Vergani, Patrizia, Cuttin, Serena, Doi, Patrizia, Bulfamante, Gaetano, Copp, Andrew J., Greene, Nicholas D. E.
Publicado no Birth Defects Res (2019)

Integrin-Mediated Focal Anchorage Drives Epithelial Zippering during Mouse Neural Tube Closure

Por Molè, Matteo A., Galea, Gabriel L., Rolo, Ana, Weberling, Antonia, Nychyk, Oleksandr, De Castro, Sandra C., Savery, Dawn, Fässler, Reinhard, Ybot-González, Patricia, Greene, Nicholas D.E., Copp, Andrew J.
Publicado no Dev Cell (2020)

Overexpression of Grainyhead-like 3 causes spina bifida and interacts genetically with mutant alleles of Grhl2 and Vangl2 in mice

Por De Castro, Sandra C P, Gustavsson, Peter, Marshall, Abigail R, Gordon, William M, Galea, Gabriel, Nikolopoulou, Evanthia, Savery, Dawn, Rolo, Ana, Stanier, Philip, Andersen, Bogi, Copp, Andrew J, Greene, Nicholas D E
Publicado no Hum Mol Genet (2018)

Diffusion microscopic MRI of the mouse embryo: Protocol and practical implementation in the splotch mouse model

Por Norris, Francesca C., Siow, Bernard M., Cleary, Jon O., Wells, Jack A., De Castro, Sandra C.P., Ordidge, Roger J., Greene, Nicholas D.E., Copp, Andrew J., Scambler, Peter J., Alexander, Daniel. C., Lythgoe, Mark F.
Publicado no Magn Reson Med (2014)

Over-expression of Grhl2 causes spina bifida in the Axial defects mutant mouse

Por Brouns, Madeleine R., De Castro, Sandra C.P., Terwindt-Rouwenhorst, Els A., Massa, Valentina, Hekking, Johan W., Hirst, Caroline S., Savery, Dawn, Munts, Chantal, Partridge, Darren, Lamers, Wout, Köhler, Eleonore, van Straaten, Henny W., Copp, Andrew J., Greene, Nicholas D.E.
Publicado em 2011

SOX2 Plays a Critical Role in the Pituitary, Forebrain, and Eye during Human Embryonic Development

Por Kelberman, Daniel, de Castro, Sandra C. P., Huang, Shuwen, Crolla, John A., Palmer, Rodger, Gregory, John W., Taylor, David, Cavallo, Luciano, Faienza, Maria F., Fischetto, Rita, Achermann, John C., Martinez-Barbera, Juan Pedro, Rizzoti, Karine, Lovell-Badge, Robin, Robinson, Iain C. A. F., Gerrelli, Dianne, Dattani, Mehul T.
Publicado em 2008

Mutations in Radial Spoke Head Protein Genes RSPH9 and RSPH4A Cause Primary Ciliary Dyskinesia with Central-Microtubular-Pair Abnormalities

Por Castleman, Victoria H., Romio, Leila, Chodhari, Rahul, Hirst, Robert A., de Castro, Sandra C.P., Parker, Keith A., Ybot-Gonzalez, Patricia, Emes, Richard D., Wilson, Stephen W., Wallis, Colin, Johnson, Colin A., Herrera, Rene J., Rutman, Andrew, Dixon, Mellisa, Shoemark, Amelia, Bush, Andrew, Hogg, Claire, Gardiner, R. Mark, Reish, Orit, Greene, Nicholas D.E., O'Callaghan, Christopher, Purton, Saul, Chung, Eddie M.K., Mitchison, Hannah M.
Publicado em 2009

Mutations in ZMYND10, a Gene Essential for Proper Axonemal Assembly of Inner and Outer Dynein Arms in Humans and Flies, Cause Primary Ciliary Dyskinesia

Por Moore, Daniel J., Onoufriadis, Alexandros, Shoemark, Amelia, Simpson, Michael A., zur Lage, Petra I., de Castro, Sandra C., Bartoloni, Lucia, Gallone, Giuseppe, Petridi, Stavroula, Woollard, Wesley J., Antony, Dinu, Schmidts, Miriam, Didonna, Teresa, Makrythanasis, Periklis, Bevillard, Jeremy, Mongan, Nigel P., Djakow, Jana, Pals, Gerard, Lucas, Jane S., Marthin, June K., Nielsen, Kim G., Santoni, Federico, Guipponi, Michel, Hogg, Claire, Antonarakis, Stylianos E., Emes, Richard D., Chung, Eddie M.K., Greene, Nicholas D.E., Blouin, Jean-Louis, Jarman, Andrew P., Mitchison, Hannah M.
Publicado em 2013