Glycine Cleavage System H Protein Is Essential for Embryonic Viability, Implying Additional Function Beyond the Glycine Cleavage System

Glycine cleavage system H protein (GCSH) is a component of the glycine cleavage system (GCS), a conserved protein complex that acts to decarboxylate glycine. Mutation of AMT or GLDC, encoding the GCS components aminomethyltransferase and glycine decarboxylase, can cause malformations of the developi...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Leung, Kit-Yi, De Castro, Sandra C. P., Galea, Gabriel L., Copp, Andrew J., Greene, Nicholas D. E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7868403/
https://ncbi.nlm.nih.gov/pubmed/33569080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.625120
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