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Neural tube closure depends on expression of Grainyhead-like 3 in multiple tissues
Failure of neural tube closure leads to neural tube defects (NTDs), common congenital abnormalities in humans. Among the genes whose loss of function causes NTDs in mice, Grainyhead-like3 (Grhl3) is essential for spinal neural tube closure, with null mutants exhibiting fully penetrant spina bifida....
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| Udgivet i: | Dev Biol |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5854268/ https://ncbi.nlm.nih.gov/pubmed/29397878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2018.01.016 |
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