Neural tube closure depends on expression of Grainyhead-like 3 in multiple tissues

Failure of neural tube closure leads to neural tube defects (NTDs), common congenital abnormalities in humans. Among the genes whose loss of function causes NTDs in mice, Grainyhead-like3 (Grhl3) is essential for spinal neural tube closure, with null mutants exhibiting fully penetrant spina bifida....

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Dev Biol
Main Authors: De Castro, Sandra C.P., Hirst, Caroline S., Savery, Dawn, Rolo, Ana, Lickert, Heiko, Andersen, Bogi, Copp, Andrew J., Greene, Nicholas D.E.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2018
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854268/
https://ncbi.nlm.nih.gov/pubmed/29397878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2018.01.016
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares