Over-expression of Grhl2 causes spina bifida in the Axial defects mutant mouse

Cranial neural tube defects (NTDs) occur in mice carrying mutant alleles of many different genes, whereas isolated spinal NTDs (spina bifida) occur in fewer models, despite being common human birth defects. Spina bifida occurs at high frequency in the Axial defects (Axd) mouse mutant but the causati...

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Egile Nagusiak: Brouns, Madeleine R., De Castro, Sandra C.P., Terwindt-Rouwenhorst, Els A., Massa, Valentina, Hekking, Johan W., Hirst, Caroline S., Savery, Dawn, Munts, Chantal, Partridge, Darren, Lamers, Wout, Köhler, Eleonore, van Straaten, Henny W., Copp, Andrew J., Greene, Nicholas D.E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2011
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063985/
https://ncbi.nlm.nih.gov/pubmed/21262862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr031
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