In Vitro Drug Combination Studies of Letermovir (AIC246, MK-8228) with Approved Anti-Human Cytomegalovirus (HCMV) and Anti-HIV Compounds in Inhibition of HCMV and HIV Replication

Por Wildum, Steffen, Zimmermann, Holger, Lischka, Peter
Publicado no Antimicrob Agents Chemother (2015)

The Human Papillomavirus Type 16 E6 Oncoprotein Can Down-Regulate p53 Activity by Targeting the Transcriptional Coactivator CBP/p300

Por Zimmermann, Holger, Degenkolbe, Roland, Bernard, Hans-Ulrich, O’Connor, Mark J.
Publicado em 1999

In Vitro and In Vivo Activities of AIC292, a Novel HIV-1 Nonnucleoside Reverse Transcriptase Inhibitor

Por Wildum, Steffen, Paulsen, Daniela, Thede, Kai, Ruebsamen-Schaeff, Helga, Zimmermann, Holger
Publicado em 2013

Geno- and Phenotypic Characterization of Human Cytomegalovirus Mutants Selected In Vitro after Letermovir (AIC246) Exposure

Por Goldner, Thomas, Hempel, Christine, Ruebsamen-Schaeff, Helga, Zimmermann, Holger, Lischka, Peter
Publicado em 2014

Dependence of Echovirus 9 on the Enterovirus RNA Replication Inhibitor 2-(α-Hydroxybenzyl)-Benzimidazole Maps to Nonstructural Protein 2C

Por Hadaschik, Dirk, Klein, Marcus, Zimmermann, Holger, Eggers, Hans J., Nelsen-Salz, Birgit
Publicado em 1999

Female preferences for male traits and territory characteristics in the cichlid fish Tropheus moorii

Por Hermann, Caroline M., Brudermann, Verena, Zimmermann, Holger, Vollmann, Johann, Sefc, Kristina M.
Publicado no Hydrobiologia (2015)

Characterization of an E1A-CBP Interaction Defines a Novel Transcriptional Adapter Motif (TRAM) in CBP/p300

Por O’Connor, Mark J., Zimmermann, Holger, Nielsen, Søren, Bernard, Hans-Ulrich, Kouzarides, Tony
Publicado em 1999

The Novel Anticytomegalovirus Compound AIC246 (Letermovir) Inhibits Human Cytomegalovirus Replication through a Specific Antiviral Mechanism That Involves the Viral Terminase

Por Goldner, Thomas, Hewlett, Guy, Ettischer, Nicole, Ruebsamen-Schaeff, Helga, Zimmermann, Holger, Lischka, Peter
Publicado em 2011

A Novel YY1-Independent Silencer Represses the Activity of the Human Papillomavirus Type 16 Enhancer

Por O’Connor, Mark J., Stünkel, Walter, Zimmermann, Holger, Koh, Choon-Heng, Bernard, Hans-Ulrich
Publicado em 1998

The Differentiation-Specific Factor CDP/Cut Represses Transcription and Replication of Human Papillomaviruses through a Conserved Silencing Element

Por O'Connor, Mark J., Stünkel, Walter, Koh, Choon-Heng, Zimmermann, Holger, Bernard, Hans-Ulrich
Publicado em 2000

In Vitro Evaluation of the Activities of the Novel Anticytomegalovirus Compound AIC246 (Letermovir) against Herpesviruses and Other Human Pathogenic Viruses

Por Marschall, Manfred, Stamminger, Thomas, Urban, Andreas, Wildum, Steffen, Ruebsamen-Schaeff, Helga, Zimmermann, Holger, Lischka, Peter
Publicado em 2012

In Vitro and In Vivo Activities of the Novel Anticytomegalovirus Compound AIC246

Por Lischka, Peter, Hewlett, Guy, Wunberg, Tobias, Baumeister, Judith, Paulsen, Daniela, Goldner, Thomas, Ruebsamen-Schaeff, Helga, Zimmermann, Holger
Publicado em 2010

Pharmacokinetics and safety of the anti‐human cytomegalovirus drug letermovir in subjects with hepatic impairment

Por Kropeit, Dirk, McCormick, David, Erb‐Zohar, Katharina, Moiseev, Valentin S., Kobalava, Zhanna D., Stobernack, Hans‐Peter, Zimmermann, Holger, Rübsamen‐Schaeff, Helga
Publicado no Br J Clin Pharmacol (2017)

Pharmacokinetics-Pharmacodynamics of the Helicase-Primase Inhibitor Pritelivir following Treatment of Wild-Type or Pritelivir-Resistant Virus Infection in a Murine Herpes Simplex V...

Por Biswas, Subhajit, Sukla, Soumi, Goldner, Thomas, Field, Hugh J., Kropeit, Dirk, Paulsen, Daniela, Welbers, André, Ruebsamen-Schaeff, Helga, Zimmermann, Holger, Birkmann, Alexander
Publicado em 2014

Asymmetric dominance and asymmetric mate choice oppose premating isolation after allopatric divergence

Por Sefc, Kristina M, Hermann, Caroline M, Steinwender, Bernd, Brindl, Hanna, Zimmermann, Holger, Mattersdorfer, Karin, Postl, Lisbeth, Makasa, Lawrence, Sturmbauer, Christian, Koblmüller, Stephan
Publicado no Ecol Evol (2015)

Efficacy of Pritelivir and Acyclovir in the Treatment of Herpes Simplex Virus Infections in a Mouse Model of Herpes Simplex Encephalitis

Por Quenelle, Debra C., Birkmann, Alexander, Goldner, Thomas, Pfaff, Tamara, Zimmermann, Holger, Bonsmann, Susanne, Collins, Deborah J., Rice, Terri L., Prichard, Mark N.
Publicado no Antiviral Res (2017)

Pharmacokinetics and safety of letermovir, a novel anti‐human cytomegalovirus drug, in patients with renal impairment

Por Kropeit, Dirk, Scheuenpflug, Jürgen, Erb‐Zohar, Katharina, Halabi, Atef, Stobernack, Hans‐Peter, Hulskotte, Ellen G. J., van Schanke, Arne, Zimmermann, Holger, Rübsamen‐Schaeff, Helga
Publicado no Br J Clin Pharmacol (2017)

No Evidence of Pritelivir Resistance Among Herpes Simplex Virus Type 2 Isolates After 4 Weeks of Daily Therapy

Por Edlefsen, Paul T., Birkmann, Alexander, Huang, Meei-Li, Magaret, Craig A., Kee, Jia Jin, Diem, Kurt, Goldner, Thomas, Timmler, Burkhard, Stoelben, Susanne, Ruebsamen-Schaeff, Helga, Zimmermann, Holger, Warren, Terri, Wald, Anna, Corey, Lawrence
Publicado no J Infect Dis (2016)

Mathematical modeling of herpes simplex virus-2 suppression with pritelivir predicts trial outcomes

Por Schiffer, Joshua T., Swan, David A., Magaret, Amalia, Corey, Lawrence, Wald, Anna, Ossig, Joachim, Ruebsamen-Schaeff, Helga, Stoelben, Susanne, Timmler, Burkhard, Zimmermann, Holger, Melhem, Murad R., Van Wart, Scott A., Rubino, Christopher M., Birkmann, Alexander
Publicado no Sci Transl Med (2016)