In Vitro and In Vivo Activities of AIC292, a Novel HIV-1 Nonnucleoside Reverse Transcriptase Inhibitor

Por Wildum, Steffen, Paulsen, Daniela, Thede, Kai, Ruebsamen-Schaeff, Helga, Zimmermann, Holger
Publicado em 2013

Geno- and Phenotypic Characterization of Human Cytomegalovirus Mutants Selected In Vitro after Letermovir (AIC246) Exposure

Por Goldner, Thomas, Hempel, Christine, Ruebsamen-Schaeff, Helga, Zimmermann, Holger, Lischka, Peter
Publicado em 2014

AIC649 Induces a Bi-Phasic Treatment Response in the Woodchuck Model of Chronic Hepatitis B

Por Paulsen, Daniela, Weber, Olaf, Ruebsamen-Schaeff, Helga, Tennant, Bud C., Menne, Stephan
Publicado no PLoS One (2015)

The Novel Anticytomegalovirus Compound AIC246 (Letermovir) Inhibits Human Cytomegalovirus Replication through a Specific Antiviral Mechanism That Involves the Viral Terminase

Por Goldner, Thomas, Hewlett, Guy, Ettischer, Nicole, Ruebsamen-Schaeff, Helga, Zimmermann, Holger, Lischka, Peter
Publicado em 2011

In Vitro Evaluation of the Activities of the Novel Anticytomegalovirus Compound AIC246 (Letermovir) against Herpesviruses and Other Human Pathogenic Viruses

Por Marschall, Manfred, Stamminger, Thomas, Urban, Andreas, Wildum, Steffen, Ruebsamen-Schaeff, Helga, Zimmermann, Holger, Lischka, Peter
Publicado em 2012

In Vitro and In Vivo Activities of the Novel Anticytomegalovirus Compound AIC246

Por Lischka, Peter, Hewlett, Guy, Wunberg, Tobias, Baumeister, Judith, Paulsen, Daniela, Goldner, Thomas, Ruebsamen-Schaeff, Helga, Zimmermann, Holger
Publicado em 2010

Pharmacokinetics-Pharmacodynamics of the Helicase-Primase Inhibitor Pritelivir following Treatment of Wild-Type or Pritelivir-Resistant Virus Infection in a Murine Herpes Simplex V...

Por Biswas, Subhajit, Sukla, Soumi, Goldner, Thomas, Field, Hugh J., Kropeit, Dirk, Paulsen, Daniela, Welbers, André, Ruebsamen-Schaeff, Helga, Zimmermann, Holger, Birkmann, Alexander
Publicado em 2014

Inactivated Orf Virus Shows Antifibrotic Activity and Inhibits Human Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) Replication in Preclinical Models

Por Paulsen, Daniela, Urban, Andreas, Knorr, Andreas, Hirth-Dietrich, Claudia, Siegling, Angela, Volk, Hans-Dieter, Mercer, Andrew A., Limmer, Andreas, Schumak, Beatrix, Knolle, Percy, Ruebsamen-Schaeff, Helga, Weber, Olaf
Publicado em 2013

No Evidence of Pritelivir Resistance Among Herpes Simplex Virus Type 2 Isolates After 4 Weeks of Daily Therapy

Por Edlefsen, Paul T., Birkmann, Alexander, Huang, Meei-Li, Magaret, Craig A., Kee, Jia Jin, Diem, Kurt, Goldner, Thomas, Timmler, Burkhard, Stoelben, Susanne, Ruebsamen-Schaeff, Helga, Zimmermann, Holger, Warren, Terri, Wald, Anna, Corey, Lawrence
Publicado no J Infect Dis (2016)

Mathematical modeling of herpes simplex virus-2 suppression with pritelivir predicts trial outcomes

Por Schiffer, Joshua T., Swan, David A., Magaret, Amalia, Corey, Lawrence, Wald, Anna, Ossig, Joachim, Ruebsamen-Schaeff, Helga, Stoelben, Susanne, Timmler, Burkhard, Zimmermann, Holger, Melhem, Murad R., Van Wart, Scott A., Rubino, Christopher M., Birkmann, Alexander
Publicado no Sci Transl Med (2016)