In Vitro Evaluation of the Activities of the Novel Anticytomegalovirus Compound AIC246 (Letermovir) against Herpesviruses and Other Human Pathogenic Viruses

AIC246 (letermovir) is a potent anticytomegalovirus drug in clinical development. Here, we report a consistent antiviral efficacy of AIC246 against human cytomegalovirus laboratory strains, clinical isolates, and virus variants resistant to approved drugs. Furthermore, we describe a remarkable selec...

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Détails bibliographiques
Auteurs principaux: Marschall, Manfred, Stamminger, Thomas, Urban, Andreas, Wildum, Steffen, Ruebsamen-Schaeff, Helga, Zimmermann, Holger, Lischka, Peter
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
Sujets:
Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264222/
https://ncbi.nlm.nih.gov/pubmed/22106211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05908-11
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