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Pharmacokinetics and safety of the anti‐human cytomegalovirus drug letermovir in subjects with hepatic impairment

AIMS: Human cytomegalovirus constitutes a prevalent and serious threat to immunocompromised individuals and requires new treatments. Letermovir is a novel viral‐terminase inhibitor that has demonstrated prophylactic/pre‐emptive activity against human cytomegalovirus in Phase 2 and 3 transplant trial...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Kropeit, Dirk, McCormick, David, Erb‐Zohar, Katharina, Moiseev, Valentin S., Kobalava, Zhanna D., Stobernack, Hans‐Peter, Zimmermann, Holger, Rübsamen‐Schaeff, Helga
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698571/
https://ncbi.nlm.nih.gov/pubmed/28722153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13376
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