Evidence of effectiveness: How much can we extrapolate from existing studies?

द्वारा Lee, Howard, Yim, Dong-Seok, Zhou, Honghui, Peck, Carl C.
प्रकाशित 2005

Development of a Physiologically Based Pharmacokinetic Model to Predict Disease-Mediated Therapeutic Protein–Drug Interactions: Modulation of Multiple Cytochrome P450 Enzymes by In...

द्वारा Jiang, Xiling, Zhuang, Yanli, Xu, Zhenhua, Wang, Weirong, Zhou, Honghui
में प्रकाशित AAPS J (2016)

Semipolar r-plane ZnO films on Si(100) substrates: Thin film epitaxy and optical properties

द्वारा Aggarwal, Ravi, Zhou, Honghui, Jin, Chunming, Narayan, J., Narayan, Roger J.
प्रकाशित 2010

Minimal physiologically-based pharmacokinetic (mPBPK) model for a monoclonal antibody against interleukin-6 in mice with collagen-induced arthritis

द्वारा Chen, Xi, Jiang, Xiling, Jusko, William J., Zhou, Honghui, Wang, Weirong
में प्रकाशित J Pharmacokinet Pharmacodyn (2016)

Risk factors for candida infection of the genital tract in the tropics

द्वारा Dou, Na, Li, Weiping, Zhao, Enfeng, Wang, Chan, Xiao, Zhaozhao, Zhou, Honghui
में प्रकाशित Afr Health Sci (2014)

Cross-arm binding efficiency of an EGFR x c-Met bispecific antibody

द्वारा Zheng, Songmao, Moores, Sheri, Jarantow, Stephen, Pardinas, Jose, Chiu, Mark, Zhou, Honghui, Wang, Weirong
में प्रकाशित MAbs (2016)

A minimal physiologically based pharmacokinetic model to characterize colon TNF suppression and treatment effects of an anti-TNF monoclonal antibody in a mouse inflammatory bowel d...

द्वारा Zheng, Songmao, Niu, Jin, Geist, Brian, Fink, Damien, Xu, Zhenhua, Zhou, Honghui, Wang, Weirong
में प्रकाशित MAbs (2020)

Translational Model‐Informed Dose Selection for a Human Positron Emission Tomography Imaging Study of JNJ‐54175446, a P2X7 Receptor Antagonist

द्वारा Xu, Yan, Miao, Xin, Ravenstijn, Paulien, Hijzen, Anja, Schmidt, Mark E., Nandy, Partha, Zhou, Honghui
में प्रकाशित Clin Transl Sci (2019)

Mechanistic Pharmacokinetic/Target Engagement/Pharmacodynamic (PK/TE/PD) Modeling in Deciphering Interplay Between a Monoclonal Antibody and Its Soluble Target in Cynomolgus Monkey...

द्वारा Wang, Weirong, Wang, Xiaofeng, Doddareddy, Rajitha, Fink, Damien, McIntosh, Thomas, Davis, Hugh M., Zhou, Honghui
प्रकाशित 2013

Population PK and PK/PD modelling of microencapsulated octreotide acetate in healthy subjects

द्वारा Zhou, Honghui, Chen, Tian-Ling, Marino, Mark, Lau, Henry, Miller, Thomas, Kalafsky, Gaetana, McLeod, James F
प्रकाशित 2000

Evaluating Potential Disease‐Mediated Protein‐Drug Interactions in Patients With Moderate‐to‐Severe Plaque Psoriasis Receiving Subcutaneous Guselkumab

द्वारा Zhu, Yaowei, Xu, Yan, Zhuang, Yanli, Piantone, Alexa, Shu, Cathye, Chen, Dion, Zhou, Honghui, Xu, Zhenhua, Sharma, Amarnath
में प्रकाशित Clin Transl Sci (2020)

Population pharmacokinetic analysis of infliximab in patients with ulcerative colitis

द्वारा Fasanmade, Adedigbo A., Adedokun, Omoniyi J., Ford, Joyce, Hernandez, Danika, Johanns, Jewel, Hu, Chuanpu, Davis, Hugh M., Zhou, Honghui
प्रकाशित 2009

Full covariate modelling approach in population pharmacokinetics: understanding the underlying hypothesis tests and implications of multiplicity

द्वारा Xu, Xu Steven, Yuan, Min, Zhu, Hao, Yang, Yaning, Wang, Hui, Zhou, Honghui, Xu, Jinfeng, Zhang, Liping, Pinheiro, Jose
में प्रकाशित Br J Clin Pharmacol (2018)

Pharmacokinetics, pharmacodynamics and safety of a human anti-IL-6 monoclonal antibody (sirukumab) in healthy subjects in a first-in-human study

द्वारा Xu, Zhenhua, Bouman-Thio, Esther, Comisar, Craig, Frederick, Bart, Van Hartingsveldt, Bart, Marini, Joseph C, Davis, Hugh M, Zhou, Honghui
प्रकाशित 2011

Whole‐exome sequencing identified two novel mutations of DYNC2LI1 in fetal skeletal ciliopathy

द्वारा Zhang, Xinyue, You, Yanqin, Xie, Xiaoxiao, Xu, Hong, Zhou, Honghui, Lei, Yuanmei, Sun, Pei, Meng, Yuanguang, Wang, Longxia, Lu, Yanping
में प्रकाशित Mol Genet Genomic Med (2020)

Therapeutic Protein Drug–Drug Interactions: Navigating the Knowledge Gaps–Highlights from the 2012 AAPS NBC Roundtable and IQ Consortium/FDA Workshop

द्वारा Kenny, Jane R., Liu, Maggie M., Chow, Andrew T., Earp, Justin C., Evers, Raymond, Slatter, J. Greg, Wang, Diane D., Zhang, Lei, Zhou, Honghui
प्रकाशित 2013

A Novel Approach to Evaluate the Pharmacokinetic Biocomparability of a Monoclonal Antibody Derived from Two Different Cell Lines Using Simultaneous Crossover Design

द्वारा Han, Chao, McIntosh, Thomas S., Geist, Brian J., Jiao, Trina, Puchalski, Thomas A., Goldberg, Kenneth M., Yang, Tong-Yuan, Pendley, Charles E., Zhou, Honghui, Davis, Hugh M.
प्रकाशित 2013

Pharmacokinetics of Daratumumab Following Intravenous Infusion in Relapsed or Refractory Multiple Myeloma After Prior Proteasome Inhibitor and Immunomodulatory Drug Treatment

द्वारा Clemens, Pamela L., Yan, Xiaoyu, Lokhorst, Henk M., Lonial, Sagar, Losic, Nedjad, Khan, Imran, Jansson, Richard, Ahmadi, Tahamtan, Lantz, Kristen, Zhou, Honghui, Puchalski, Thomas, Xu, Xu Steven
में प्रकाशित Clin Pharmacokinet (2016)

Titin and Diaphragm Dysfunction in Chronic Obstructive Pulmonary Disease

द्वारा Ottenheijm, Coen A. C., Heunks, Leo M. A., Hafmans, Theo, van der Ven, Peter F. M., Benoist, Caroline, Zhou, Honghui, Labeit, Siegfried, Granzier, Henk L., Dekhuijzen, P. N. Richard
प्रकाशित 2006

Pharmacokinetics and Exposure-response Relationship of Golimumab in Patients with Moderately-to-Severely Active Ulcerative Colitis: Results from Phase 2/3 PURSUIT Induction and Mai...

द्वारा Adedokun, Omoniyi J., Xu, Zhenhua, Marano, Colleen W., Strauss, Richard, Zhang, Hongyan, Johanns, Jewel, Zhou, Honghui, Davis, Hugh M., Reinisch, Walter, Feagan, Brian G., Rutgeerts, Paul, Sandborn, William J.
में प्रकाशित J Crohns Colitis (2017)