Design of next-generation therapeutic IgG4 with improved manufacturability and bioanalytical characteristics

Por Zhiqiang Chen, Yueming Qian, Yuanli Song, Xuankuo Xu, Li Tao, Nesredin Mussa, Sanchayita Ghose, Zheng Jian Li
Publicado em 2020-01-01

N-1 Perfusion Platform Development Using a Capacitance Probe for Biomanufacturing

Por Emily S. C. Rittershaus, Matthew S. Rehmann, Jianlin Xu, Qin He, Charles Hill, Jeffrey Swanberg, Michael C. Borys, Zheng-Jian Li, Anurag Khetan
Publicado em 2022-03-01

Optimization and kinetic modeling of interchain disulfide bond reoxidation of monoclonal antibodies in bioprocesses

Por Peifeng Tang, Zhijun Tan, Vivekh Ehamparanathan, Tingwei Ren, Laurel Hoffman, Cheng Du, Yuanli Song, Li Tao, Angela Lewandowski, Sanchayita Ghose, Zheng Jian Li, Shijie Liu
Publicado em 2020-01-01

Isolation from Ochrobactrum anthropi of a Novel Class II 5-Enopyruvylshikimate-3-Phosphate Synthase with High Tolerance to Glyphosate

Por Tian, Yong-Sheng, Xiong, Ai-Sheng, Xu, Jing, Zhao, Wei, Gao, Feng, Fu, Xiao-Yan, Xu, Hu, Zheng, Jian-Li, Peng, Ri-He, Yao, Quan-Hong
Publicado em 2010

Biomanufacturing evolution from conventional to intensified processes for productivity improvement: a case study

Por Jianlin Xu, Xuankuo Xu, Chao Huang, James Angelo, Christopher L. Oliveira, Mengmeng Xu, Xia Xu, Deniz Temel, Julia Ding, Sanchayita Ghose, Michael C. Borys, Zheng Jian Li
Publicado em 2020-01-01

On-column disulfide bond formation of monoclonal antibodies during Protein A chromatography eliminates low molecular weight species and rescues reduced antibodies

Por Zhijun Tan, Vivekh Ehamparanathan, Tingwei Ren, Peifeng Tang, Laurel Hoffman, June Kuang, Peiran Liu, Chao Huang, Cheng Du, Li Tao, Letha Chemmalil, Angela Lewandowski, Sanchayita Ghose, Zheng Jian Li, Shijie Liu
Publicado em 2020-01-01

Improved Titer in Late-Stage Mammalian Cell Culture Manufacturing by Re-Cloning

Por Qin He, Matthew S. Rehmann, Jun Tian, Jianlin Xu, Luzmary Sabino, Erik Vandermark, Ziev Basson, Iris Po, Kathleen Bierilo, Gabi Tremml, Giovanni Rizzi, Erik F. Langsdorf, Nan-Xin Qian, Michael C. Borys, Anurag Khetan, Zheng-Jian Li
Publicado em 2022-04-01