Histone deacetylases 1 and 2 cooperate in regulating BRCA1, CHK1, and RAD51 expression in acute myeloid leukemia cells

Por Zhao, Jianyun, Xie, Chengzhi, Edwards, Holly, Wang, Guan, Taub, Jeffrey W, Ge, Yubin
Publicado no Oncotarget (2016)

Inhibition of CHK1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells

Por Zhao, Jianyun, Niu, Xiaojia, Li, Xinyu, Edwards, Holly, Wang, Guan, Wang, Yue, Taub, Jeffrey W, Lin, Hai, Ge, Yubin
Publicado no Oncotarget (2016)

Targeting PI3K, mTOR, ERK, and Bcl-2 signaling network shows superior antileukemic activity against AML ex vivo

Por Su, Yongwei, Li, Xinyu, Ma, Jun, Zhao, Jianyun, Liu, Shuang, Wang, Guan, Edwards, Holly, Taub, Jeffrey W., Lin, Hai, Ge, Yubin
Publicado no Biochem Pharmacol (2017)

Inhibition of Mcl-1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells

Por Luedtke, Daniel A, Niu, Xiaojia, Pan, Yihang, Zhao, Jianyun, Liu, Shuang, Edwards, Holly, Chen, Kang, Lin, Hai, Taub, Jeffrey W, Ge, Yubin
Publicado no Signal Transduct Target Ther (2017)

Class I and Class II Histone Deacetylases Are Potential Therapeutic Targets for Treating Pancreatic Cancer

Por Wang, Guan, He, Jing, Zhao, Jianyun, Yun, Wenting, Xie, Chengzhi, Taub, Jeffrey W., Azmi, Asfar, Mohammad, Ramzi M., Dong, Yan, Kong, Wei, Guo, Yingjie, Ge, Yubin
Publicado em 2012

Binding of released Bim to Mcl-1 is a mechanism of intrinsic resistance to ABT-199 which can be overcome by combination with daunorubicin or cytarabine in AML cells

Por Niu, Xiaojia, Zhao, Jianyun, Ma, Jun, Xie, Chengzhi, Edwards, Holly, Wang, Guan, Caldwell, J. Timothy, Xiang, Shengyan, Zhang, Xiaohong, Chu, Roland, Wang, Zhihong, Lin, Hai, Taub, Jeffrey W., Ge, Yubin
Publicado no Clin Cancer Res (2016)

Mechanisms responsible for the synergistic antileukemic interactions between ATR inhibition and cytarabine in acute myeloid leukemia cells

Por Ma, Jun, Li, Xinyu, Su, Yongwei, Zhao, Jianyun, Luedtke, Daniel A., Epshteyn, Valeria, Edwards, Holly, Wang, Guan, Wang, Zhihong, Chu, Roland, Taub, Jeffrey W., Lin, Hai, Wang, Yue, Ge, Yubin
Publicado no Sci Rep (2017)

A CHAF1B-dependent molecular switch in hematopoiesis and leukemia pathogenesis

Por Volk, Andrew, Liang, Kaiwei, Suraneni, Praveen, Li, Xinyu, Zhao, Jianyun, Bulic, Marinka, Marshall, Stacy, Pulakanti, Kirthi, Malinge, Sebastien, Taub, Jeffrey, Ge, Yubin, Rao, Sridhar, Bartom, Elizabeth, Shilatifard, Ali, Crispino, John D
Publicado no Cancer Cell (2018)