Class I and Class II Histone Deacetylases Are Potential Therapeutic Targets for Treating Pancreatic Cancer

BACKGROUND: Pancreatic cancer is a highly malignant disease with an extremely poor prognosis. Histone deacetylase inhibitors (HDACIs) have shown promising antitumor activities against preclinical models of pancreatic cancer, either alone or in combination with chemotherapeutic agents. In this study,...

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Detalhes bibliográficos
Main Authors: Wang, Guan, He, Jing, Zhao, Jianyun, Yun, Wenting, Xie, Chengzhi, Taub, Jeffrey W., Azmi, Asfar, Mohammad, Ramzi M., Dong, Yan, Kong, Wei, Guo, Yingjie, Ge, Yubin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522644/
https://ncbi.nlm.nih.gov/pubmed/23251689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052095
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